AnestAssist usage and background information can be found in a
number of locations
on this site. Topics include
- Q. What drug
interactions are calculated?
AnestAssist PK/PD calculates the combined effect (sedation and/or
analgesia) probability for propofol, sevoflurane, or isoflurane interacting with remifentanil or
any of it's congeners fentanyl, alfentanil, and sufentanil. For details
please see AnestAssist
- Q. How are drug
Clinical researchers construct 3D response surface models, which
basically give the response (effect probability) over a range of effect
site concentrations of a pair of drugs in combination. AnestAssist uses
a propofol-remifentanil response surface model for which references can
be found here: AnestAssist
- Q. How long can a
case simulation be?
- A. Cases with a "real-time" time base may be 48 hrs, cases with a "smulation" time base may be 24 hrs. From a practical point
of view, the longer the case the longer the recalculation time. It
takes less than a second to calculate 1 hour of a propofol+remifentanil
case. A 12 hour case of propofol+remifentanil takes about 10 seconds to
completely calculate on an iPhone 3G. However, when a drug is entered
AnestAssist only recalculates from the time the drug was given to 2
hours in the future, so you will normally not see recalculation times
more than about 1 or 2 seconds no matter how long the case is.
- Q. How many drug
given entries can I enter?
There is no limit on the number of drug entries imposed by AnestAssist,
nor do the number of entries have any significant effect on calculation
times. The main determinant of calculation time is total case length
- Q. How many case
files can I store?
There is no limit on the number of cases you can store imposed by
AnestAssist. Case files are very small, just patient info and the drug
given list are stored (the PK/PD graphs are recalculated when the case
is opened). A case file is typically less than 1000 bytes, so you could
store 1000 cases and only use 1 MB!